Koichi Kawakami

The paper identifies an osmo-hydraulic volume-regulation mechanism in haemogenic endothelial cells during endothelial-to-haematopoietic transition, showing it maintains cell integrity and HSPC production.

The paper uses CaMPARI-seq to identify neuronal subtypes in the zebrafish pretectum involved in distinguishing optic flow patterns for different behaviors.

The paper identifies a thalamocortical-like pathway in zebrafish, showing topographically organized sensory processing in the pallium with increasing complexity along the posterior-anterior axis.

The paper identifies large spinal motor neurons as highly autophagic and shows that their enhanced degradation is neuroprotective in ALS.

The paper identifies three novel candidate genes for ocular congenital cranial dysinnervation disorders using zebrafish CRISPR screening and protein binding microarrays to assess variant functionality.

The paper investigates how retinal input affects neurogenesis and cell-type configuration in the visual forebrain of zebrafish, finding that neurogenesis slows but cell-type configuration remains intact.

The paper identifies molecular signatures and transcription factors that determine functional subtypes of motor neurons in zebrafish, showing their role in fast MN development.

This study shows that TDP-43 overexpression reduces excitability of spinal motor neurons during fictive locomotion in zebrafish.

The paper shows that Schwann cells guide axon sorting at a nerve plexus during regeneration, restoring target-specific connectivity in zebrafish.

This study shows that loss of Eya1 disrupts CXCR7b expression, leading to abnormal collective cell chemotaxis and organ dysmorphia in a zebrafish model of branchio-oto-renal syndrome.

This study identifies context-dependent contributions of retinotectal and isthmotectal circuits to visual saliency map computation in larval zebrafish using behavioral and functional recordings.

This paper describes a deep ultraviolet light-based wide-field fluorescence microscope for 2D and 3D brain imaging, demonstrating its versatility and applicability for rodent brain studies.

The paper investigates the developmental origin of a visual relay nucleus in zebrafish, finding it arises from the midbrain rather than the forebrain, suggesting non-thalamic evolution of visual pathways.

The paper identifies a PSMC3 variant causing a neurosensory syndrome with deafness and cataracts due to proteotoxic stress and impaired proteasome function.

This study uses optogenetic tools to show that TDP-43 oligomerization in zebrafish motor neurons leads to both acute and long-term ALS-related pathologies.

This study shows that gsx2 mediates rostro-caudal positional signals to specify inferior olivary neurons from ptf1a-expressing progenitors in zebrafish.

This study identifies a bidirectional interaction between hypothalamic nuclei in larval zebrafish that regulates hunger and satiety through opposing activity patterns.

The paper investigates glia-neuron interactions during seizure transitions in zebrafish, finding that glial activity precedes and influences neuronal activity during seizures.

This paper presents a high-quality goldfish genome assembly and analyzes gene evolution after whole genome duplication, identifying gene divergence patterns across tissues.

The paper identifies protocadherin-mediated repulsion as critical for organizing the abducens nucleus's topography and neuromuscular connections in zebrafish.

The paper identifies a wound-specific notochord sheath cell subpopulation expressing Wilms Tumor 1b that forms a stopper-like structure during vertebra repair in zebrafish.

This study shows that visual prey detection activates the hypothalamic feeding centre in zebrafish via a pretecto-hypothalamic pathway.