Takuya Tomita

The paper develops CRISPR/Cas13-based tools to analyze RNA-protein interactions by integrating existing PPI methods with RNA-targeting Cas13, demonstrating their utility in studying paraspeckles.

This study shows that caveolin-1 maintains adult neural stem cell quiescence and lineage fidelity by promoting lysosomal degradation of PDGFRα.

The paper identifies the roles of Ubp2 and Ubp3 in editing polyubiquitin chains on ribosomes to maintain RQC activity.

The paper identifies large spinal motor neurons as highly autophagic and shows that their enhanced degradation is neuroprotective in ALS.