Epoxyazadiradione ameliorates Parkinson's disease by upregulating heat shock factor 1 and protein degradation pathways in mice.
Shivani Chandel, Naibedya Dutta, HOSSAINOOR RAHAMAN SARENG, Nilanjana Ghosh, Izaz Monir Kamal, Anirban Manna, V. Ravichandiran, Jayanta Mukhopadhyay, Saikat Chkrabarti, Rajiv Kumar Goswami, Mahadeb Pal
This paper identifies Epoxyazadiradione as a compound that improves Parkinson's disease symptoms in mice by enhancing heat shock factor 1 and protein degradation pathways without affecting redox balance.
bioRxiv · Dec 11, 2025 · PreprintPharmacology & Toxicology