Endocytosis of ALK promotes glucose uptake in ALK-amplified neuroblastoma
Ryouhei Tsutsumi, Shoko Hikage, Shinichi Kiyonari, Ryuichi Sakai
This study shows that ALK endocytosis promotes glucose uptake in ALK-amplified neuroblastoma cells by delivering GLUT1 to mitochondria, independent of ERK and PI3K-AKT pathways.
bioRxiv · Aug 5, 2026 · PreprintCancer Biology