Author

Ryuichi Sakai

Hokkaido UniversityORCID 0000-0001-6490-0495Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Akihiro NinomiyaiD· 1 shared Antonio EvidenteiD· 1 shared Atsushi Tsugita· 1 shared Ayato TakadaiD· 1 shared Hiroko Miyamoto· 1 shared Hiromi WatariiD· 1 shared Kazutoshi YoshitakeiD· 1 shared Ken MatsumotoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Akihiro NinomiyaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 5, 2026

Endocytosis of ALK promotes glucose uptake in ALK-amplified neuroblastoma

Ryouhei Tsutsumi, Shoko Hikage, Shinichi Kiyonari, Ryuichi Sakai

This study shows that ALK endocytosis promotes glucose uptake in ALK-amplified neuroblastoma cells by delivering GLUT1 to mitochondria, independent of ERK and PI3K-AKT pathways.

DOI 10.64898/2026.08.04.742396

humanbulk RNA-seq

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BiochemistrybioRxivPreprintDec 20, 2025

Modulation of translational elongation by montanine alkaloids preferentially inhibits RNA viruses

RYUICHI SAKAI, Kyohei Sato, Atsushi Tsugita…·Yoshikazu Tanaka

This study identifies montanine as a potent antiviral compound that inhibits RNA viruses by targeting translational elongation and GCN1-related stress responses.

1 citation

humanproteomics

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MicrobiologybioRxivPreprintDec 29, 2024

Symbiotic Bacterial Partners for Chemical Defense are Vertically Transmitted in a Marine Sponge

Masaki Fujita, Yuji Ise, Masashi Fukuoka…·Kentaro Takada

This study identifies vertical transmission of cytotoxin-producing bacteria in marine sponges through bacteriocyte-like structures.

1 citation

experimental assayhost-pathogen & immune response

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