Shoupei Liu

Structure-guided, physics-aware reconstruction expands scan-limited multiphoton imaging

SPARC improves temporal and spatial resolution in scan-limited multiphoton imaging by integrating denoising and deep upsampling with structural and physical constraints.

Kilohertz-rate two-photon voltage imaging of population dynamics in vivo

This paper introduces HS2PM, a two-photon microscope that enables kilohertz-rate imaging of neuronal populations in vivo, revealing voltage dynamics and their role in sensory adaptation and population coding.

A plug-and-play ROI imaging module and deep-learning denoising framework extend three-photon microscopy to 1.7 mm depth

This paper introduces a hardware and software solution that extends three-photon microscopy depth to 1.7 mm by improving signal-to-noise ratio and noise removal.

A Compact Two-Photon Module for Simultaneous Dual-Depth, Multi-Region in vivo Brain Imaging

This paper introduces a compact two-photon imaging module that enables simultaneous dual-depth, multi-region in vivo brain imaging, revealing context-dependent and depth-divergent neural activity patterns.

Cortex-Wide, Cellular-Resolution Volumetric Imaging with a Modular Two-Photon Imaging Platform

The paper introduces Meso2P, a two-photon imaging platform that enables high-resolution, large-scale volumetric imaging of the cortex with modular upgrades for multi-plane and optogenetic stimulation.