Longitudinal whole transcriptomic profiling of live cells through domain adaptation
Zhifei Dong, Shreya Mishra, Maha Mohamed Tageldein, Chris McIntosh, Shane M. Harding, Gregory W. Schwartz
PENNE infers whole-transcriptomic profiles from live-cell images using domain adaptation, capturing temporal gene dynamics and cell-type markers.
bioRxiv · Aug 17, 2026 · PreprintBioinformatics