Author

Sihan Hao

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anuraag BukkuriiD· 1 shared Daniel D. BrowniD· 1 shared Dante PoeiD· 1 shared Janet McLaughliniD· 1 shared Katarzyna M. KedzioraiD· 1 shared Wayne StallaertiD· 1 shared Yian YangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Anuraag BukkuriORCID

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1 paper

Recent·Most cited

Distinct p21 dynamics drive alternative routes to whole-genome duplication through a common CDK4/6-dependent polyploid G0 state

Yian Yang, Anuraag Bukkuri, Dante Poe, Janet McLaughlin, Sihan Hao, Daniel D. Brown, Katarzyna M. Kedziora, Wayne Stallaert

The paper identifies two distinct p21-driven pathways to whole-genome duplication in breast cancer cells, both converging on a CDK4/6-dependent polyploid G0 state, and shows that CDK4/6 inhibitors can block WGD and enhance therapy efficacy.

bioRxiv · Jan 15, 2026 · PreprintCell Biology