Author

Silvan Brunn

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Alessandro A. SartoriiD· 1 shared Dominik Zanetti· 1 shared Francesca VivaldaiD· 1 shared Hakan KöksaliD· 1 shared Ioana DomocosiD· 1 shared Marc NateriD· 1 shared Marco GattiiD· 1 shared Maries F. van den BroekiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alessandro A. SartoriORCID

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1 paper

Recent·Most cited

Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

Michael Herbst, Hakan Köksal, Silvan Brunn, Dominik Zanetti, Ioana Domocos, Viola De Stefani, Marco Gatti, Francesca Vivalda, Paulo Pereira, Marc Nater, Virginia Cecconi, Alessandro A. Sartori, Maries F. van den Broek

This study shows that cancer-cell-derived cGAMP both enhances and limits CD8+ T cell anti-tumor activity through STING signaling.

Cell Reports · Apr 1, 2025Peer-reviewedImmunology