Author

Sixto M. Leal

University of Alabama at Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1 Organism:rat· 1

Frequent Co-Authors

Kalai MatheeiD· 2 shared Aarón Silva-SáncheziD· 1 shared Ananda Mohan MondaliD· 1 shared Ashleigh Nichole RiegleriD· 1 shared Christian A. BalbiniD· 1 shared Christopher M. WeissiD· 1 shared Courtney A. BarkleyiD· 1 shared Davide BottaiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioinformatics

Kalai MatheeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection

Davide Botta, Michael D. Schultz, Aarón Silva-Sánchez, Davies Kalange, Jobaida Akther, Fen Zhou, Jennifer L. Tipper, Guang Yang, Levi Schaefers, Courtney A. Barkley, Shihong Qiu, Jeremy B. Foote, Mariana F. Tioni, Christopher M. Weiss, Shannon I. Phan, , Frances E. Lund

This study evaluates two RSV-vectored SARS-CoV-2 vaccines, showing they induce systemic and mucosal immunity and protect against viral challenge and natural infection.

Vaccines · Apr 29, 2026Peer-reviewedImmunology

EMoMiS: A Pipeline for Epitope-based Molecular Mimicry Search in Protein Structures with Applications to SARS-CoV-2

Vitalii Stebliankin, Rajeshwari Chellappan, Prabin Baral, Christian A. Balbin, Janelle Nunez-Castilla, Masrur Sobhan, Trevor Cickovski, Ashleigh Nichole Riegler, Ananda Mohan Mondal, Jessica Siltberg-Liberles, Prem P. Chapagain, Sathibalan Ponniah, Sixto M. Leal, Kalai Mathee, Giri Narasimhan

EMoMiS identifies molecular mimicry between SARS-CoV-2 proteins and viral/human proteins, offering insights into cross-protection and side effects.

Computational and Structural Biotechnology Journal · Jan 1, 2026Peer-reviewedBioinformatics

Characterization of L-serine deaminases, SdaA (PA2448) and SdaB (PA5379), and their potential role in Pseudomonas aeruginosa pathogenesis

Sixto M. Leal, Elaine Newman, Kalai Mathee

This study investigates the role of L-serine deaminases SdaA and SdaB in Pseudomonas aeruginosa, showing their contribution to serine utilization and virulence.

bioRxiv · Aug 20, 2018 · PreprintMicrobiology