Jobaida Akther

Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection

This study evaluates two RSV-vectored SARS-CoV-2 vaccines, showing they induce systemic and mucosal immunity and protect against viral challenge and natural infection.

Acute malaria dysregulates specialized lymph node macrophages to suppress vaccine-elicited protection against Ebola virus

This study shows that acute malaria infection reduces the effectiveness of a low-dose Ebola vaccine by impairing antibody responses in lymph node macrophages, which can be mitigated with higher vaccine doses.

Mucosal delivery of influenza antigens using a replication deficient adenovirus supports broadly reactive antibody responses and heterologous viral immunity in the respiratory tract of animals

This study shows that intranasal delivery of influenza antigens via a replication-deficient adenovirus induces broader antibody responses and better viral immunity in the respiratory tract compared to systemic delivery.