Author

Siyuan Tao

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:contrastive learning· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron R. DinneriD· 1 shared Aditya NandyiD· 1 shared Bryan C. DickinsoniD· 1 shared Cheng Frank GaoiD· 1 shared Christopher BasileiD· 1 shared Dongbo BuiD· 1 shared Haicang ZhangiD· 1 shared Joshua A. PixleyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Aaron R. DinnerORCID

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2 papers

Recent·Most cited

Mapping the diverse topologies of protein-protein interaction fitness landscapes

Shannon S. Lu, Matthew J. Styles, Cheng Frank Gao, Aditya Nandy, Christopher Basile, Joshua A. Pixley, Siyuan Tao, Aaron R. Dinner, Suriyanarayanan Vaikuntanathan, Bryan C. Dickinson

The paper identifies target-specific fitness landscapes in protein-protein interactions and develops a supervised contrastive learning approach to predict binders.

bioRxiv · Oct 14, 2025 · PreprintSynthetic Biology

Accurate structure prediction of immune proteins using parameter-efficient transfer learning

Zhu Tian, Milong Ren, Z. He, Siyuan Tao, Ming Li, Dongbo Bu, Haicang Zhang

The paper introduces ImmuneFold, a transfer learning method for immune protein structure prediction, showing improved accuracy over existing methods for TCR-epitope binding.

bioRxiv · Nov 13, 2024 · PreprintBioinformatics