Mitochondrial STAT3-mediated suppression of apoptosis constrains antimycobacterial immunity
Cory J. Mabry, Aja K. Coleman, Mackenzie H. Smith, SL Hahn, Taylor Newbolt, Morgan J. Chapman, Lauren W. Stranahan, Chi Gidley Weindel, Kristin L. Patrick, Robert O. Watson
This study identifies Trim14's role in suppressing apoptosis via mitochondrial Stat3 during Mtb infection, enhancing antimycobacterial immunity.
bioRxiv · Jul 1, 2026 · PreprintImmunology