Morgan J. Chapman

This study identifies Rv1075c as a Mycobacterium tuberculosis nucleomodulin that interacts with the SET1 histone methyltransferase complex, modulating host inflammation and lipid metabolism to promote bacterial persistence.

This study identifies Trim14's role in suppressing apoptosis via mitochondrial Stat3 during Mtb infection, enhancing antimycobacterial immunity.

This study identifies hnRNPA2B1 as a splicing regulator that modulates anti-mycobacterial immune responses in macrophages by controlling alternative splicing of Irgm1.