The RNA-binding protein RSRC2 promotes mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1
Kaliya Georgieva, Alice O. Coomer, Parnia Babaei, Giulia Guiducci, Martin Dodel, Eleni Maniati, Anisha Thind, Sneha Krishnamurthy, Anna Nawrocka, Samuel S. Wallis, Alena Shkumatava, Jun Wang, Faraz K. Mardakheh, Lovorka Stojic
This study identifies RSRC2 as a regulator of mitotic fidelity through its interaction with the lncRNA C1QTNF1-AS1, showing defects in chromosome congression when either is lost.
bioRxiv · Jan 21, 2025 · PreprintCell Biology