GWAS and 3D chromatin mapping identifies multicancer risk genes associated with hormone-dependent cancers
S. Rivera, Juliet D. French, Mainá Bitar, Haran Sivakumaran, Sneha Nair, Susanne Kaufmann, Kristine M. Hillman, Mahdi Moradi Marjaneh, Jonathan Beesley, Stacey L. Edwards
The paper identifies 44 multi-cancer risk regions across four hormone-dependent cancers using GWAS and 3D chromatin mapping, annotating 53 candidate risk genes with potential therapeutic implications.
PLoS Genetics · Nov 25, 2024Peer-reviewedGenetic & Genomic Medicine