Stacey L. Edwards

This study identifies genomic mechanisms enabling BRCA1 methylation loss and promoter bypass in ovarian cancer, leading to PARP inhibitor resistance.

HyDRA integrates long- and short-read RNAseq data to improve transcriptome assembly, identifying over 50,000 new long noncoding RNAs in ovarian and fallopian tube samples.

The paper identifies 44 multi-cancer risk regions across four hormone-dependent cancers using GWAS and 3D chromatin mapping, annotating 53 candidate risk genes with potential therapeutic implications.

The paper identifies KILR, a breast cancer risk-associated lncRNA, and shows it regulates DNA replication and repair by sequestering RPA1.

The paper maps chromatin interactions at 139 breast cancer risk signals using Capture Hi-C and identifies candidate target genes and functional mechanisms.

The paper identifies 14 genes, including NTN4, associated with breast cancer risk variants through allelic expression imbalance analysis.

The paper identifies driver genes in prostate cancer by analyzing convergence of non-coding mutations in regulatory regions using 3D chromatin interactions and genomic data.