Author

Sofia Glynne

University of California San Diego

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Biochemistry· 1

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron A. SmargoniD· 1 shared Christian R. FagreiD· 1 shared Deepak PantiD· 1 shared Gene Wei-Ming YeoiD· 1 shared Jack T. NaritomiiD· 1 shared Johnathan Nguyen· 1 shared Trent A. GombergiD· 1 shared Wendy V. GilbertiD· 1 shared

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2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Aaron A. SmargonORCID

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1 paper

Recent·Most cited

Small nuclear RNAs enhance protein-free RNA-programmable base conversion on mammalian coding transcripts

Aaron A. Smargon, Deepak Pant, Trent A. Gomberg, Christian R. Fagre, Sofia Glynne, Johnathan Nguyen, Jack T. Naritomi, Wendy V. Gilbert, Gene Wei-Ming Yeo

This study shows that guided A>I snRNAs improve RNA base conversion efficiency and reduce off-target effects compared to ADAR-recruiting circular RNAs in human cells.

Nature Chemical Biology · Sep 18, 2025Peer-reviewedBiochemistry