Fluorinated RNA origami enables serum-stable nanodevices for sensing and targeting
Emil L. Kristoffersen, Nikolaj Holck Zwergius, Néstor Sampedro Vallina, Amanda Dyrholm Stange, Lasse Messell Desdorf, Sofie Thomsen, Victoria Birkedal, Nicolas Glück, Laia Civit, Cody W. Geary, Jørgen Kjems, Julián Valero, Ebbe Sloth Andersen
This paper introduces FY-RNA origami structures that are serum-stable and capable of molecular sensing and targeting, revealing structural insights through cryo-EM and simulations.
bioRxiv · Mar 4, 2026 · PreprintBiochemistry