Ebbe Sloth Andersen

This paper introduces FY-RNA origami structures that are serum-stable and capable of molecular sensing and targeting, revealing structural insights through cryo-EM and simulations.

Structure providers for 18 CASP16 nucleic acid targets find blind predictions capture secondary structure but miss non-canonical interactions, backbone kinks, ligand sites, and intermolecular interfaces.

This study uses cryo-EM to characterize dimeric intermediates in RNA-catalyzed rolling circle synthesis, revealing their structural diversity and potential role in RNA replication.

The paper describes a method to assemble small synthetic genes with repetitive elements using Golden Gate Assembly, achieving high fidelity for challenging gene constructs.