GLE1 dysfunction compromises cellular homeostasis, spatial organization, and peripheral axon branching
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltán Szabó, Rasmus I. P. Valtonen, Mikko Paavo Tulppo, Johanna M. Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri T. Piepponen, Vootele Võikar, Juho Väänänen, , Satu Kuure
This study investigates the role of GLE1 in cellular homeostasis and development, showing that its dysfunction leads to embryonic lethality and mid-adulthood death in mice, with defects in neural crest-derived tissues and stress responses.
FEBS Journal · Jul 17, 2025Peer-reviewedDevelopmental Biology