Vootele Võikar

This study investigates the role of GLE1 in cellular homeostasis and development, showing that its dysfunction leads to embryonic lethality and mid-adulthood death in mice, with defects in neural crest-derived tissues and stress responses.

This study shows that TrkB activation in PV+ interneurons is essential for antidepressant-induced behavioral flexibility and synaptic plasticity in spatial and fear memory.