A GenoChemetic strategy for derivatization of the violacein natural product scaffold
Hung‐En Lai, Alan M. C. Obled, Soo Mei Chee, Rhodri M. L. Morgan, Rosemary Lynch, Sunil V. Sharma, Simon J. Moore, Karen Marie Polizzi, Rebecca J. M. Goss, Paul S. Freemont
The paper demonstrates a method to generate diverse halogenated and derivatized analogues of the natural product violacein using synthetic biology and chemistry.
ACS Chemical Biology · Oct 14, 2021Peer-reviewedSynthetic Biology