Mapping the dynamics of epigenetic adaptation during heterochromatin misregulation
Ajay Larkin, Colin Kunze, Melissa Seman, Alexander Levashkevich, Justin Curran, Dionysus Morris-Evans, Sophia Lemieux, Ahmad S. Khalil, Kaushik Ragunathan
This study investigates epigenetic adaptation in fission yeast by inducing H3K9me redistribution, revealing slow kinetics and memory-like behavior in chromatin and transcriptional states during stress adaptation.
bioRxiv · Jul 10, 2023 · PreprintGenetics