Kaushik Ragunathan

This study shows hydrogen sulfide increases copper uptake and localization in cells, with copper primarily in the Cu2+ state, using the ZNT1 transporter for import and ATP7A for export.

This study shows that Clr4's engagement with chromatin in S. pombe is driven by substrate recognition, not sequestration, through guided search behavior.

This study shows that the CHD remodeler Mit1 initiates heterochromatin formation and H3K9 methylation independently of Clr4, revealing a remodeler-writer feedback mechanism.

This study shows that minor amino acid changes in Swi6 can lead to significant changes in epigenetic inheritance by altering effector recruitment specificity.

This study shows that HP1 proteins are essential for maintaining heterochromatin but not for its establishment, as their function can be bypassed when specific histone modifiers are deleted.

This study investigates epigenetic adaptation in fission yeast by inducing H3K9me redistribution, revealing slow kinetics and memory-like behavior in chromatin and transcriptional states during stress adaptation.