Alexander Levashkevich

This study shows that Clr4's engagement with chromatin in S. pombe is driven by substrate recognition, not sequestration, through guided search behavior.

This study shows that minor amino acid changes in Swi6 can lead to significant changes in epigenetic inheritance by altering effector recruitment specificity.

This study shows that HP1 proteins are essential for maintaining heterochromatin but not for its establishment, as their function can be bypassed when specific histone modifiers are deleted.

This study investigates epigenetic adaptation in fission yeast by inducing H3K9me redistribution, revealing slow kinetics and memory-like behavior in chromatin and transcriptional states during stress adaptation.