The elongation of Mest transcript into MestXL sustains, but does not initiate, the maternal allele bias of its convergent gene Copg2 during neurogenesis
Sophie Perillous, Anne-Charlotte Fromaget, Céline Gonthier‐Guéret, Ornella Clerici, Marion Espenel, Alice Murigneux, Sophie Phan, Léa Feit, Catherine Vaurs‐Barrière, Floric Slimani, Céline Lemmers, Davide Normanno, Amanda Ha, Nolan Ashworth, Aaron Bogutz, , Philippe Arnaúd
The paper investigates the regulation of maternal allele bias in Copg2 during neurogenesis, showing it involves a two-step mechanism beyond MestXL-mediated interference.
Nature Communications · Sep 23, 2026Peer-reviewedMolecular Biology