Fibro-adipogenic Progenitor and Macrophage Remodeling of the Aging Skeletal Muscle Niche During Exercise-Induced Hypertrophy
Jakob Wang, Jonas Jensen, Soren Kudahl, Jesper Just, Frederik Forsberg Thybo, Mette Bjerre, Frank Vincenzo de Paoli, Niels Jessen, Kristian Vissing, Jean Farup
This study examines how exercise-induced hypertrophy in older adults alters fibro-adipogenic progenitors (FAPs) and macrophages in skeletal muscle, revealing phenotypic shifts and interactions that support muscle growth.
bioRxiv · Sep 28, 2026 · PreprintCell Biology