Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to successive stimulus.
Kira D. A. Rienecker, Robert G. Poston, Joshua S. Segales, Isabelle W. Finholm, Morgan H. Sono, Sorina J. Munteanu, Mina Ghaninejad-Esfahani, Ayna Rejepova, Susana Tejeda-Garibay, Kevin D. Wickman, Ezequiel Marrón Fernández de Velasco, Stanley A. Thayer, Ramendra N. Saha
The paper shows mild depolarization in neurons triggers immediate early genes and temporarily reduces responses to subsequent stimuli.
Journal of Biological Chemistry · Jul 18, 2022Peer-reviewedNeuroscience