Author

Sorosh Husseinzadeh

The University of Texas Medical Branch at Galveston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Angelo GaitasiD· 2 shared Bin GongiD· 2 shared Jiani Bei· 2 shared Qing ChangiD· 2 shared Xiang FangiD· 2 shared Yuan QiuiD· 2 shared Balaji KrishnaniD· 1 shared Changcheng Zhou· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Angelo GaitasORCID

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2 papers

Recent·Most cited

Identification of common sequence motifs shared exclusively among selectively packed exosomal pathogenic microRNAs during rickettsial infections

Jiani Bei, Yuan Qiu, Diane C. Cockrell, Qing Chang, Sorosh Husseinzadeh, Changcheng Zhou, Xiang Fang, Xiaoyong Bao, Yang Jin, Angelo Gaitas, Kamil Khanipov, Taís B. Saito, Bin Gong

The paper identifies common sequence motifs shared among specific microRNAs in exosomes from rickettsia-infected cells, linking them to microvasculopathy.

Journal of Cellular Physiology · Jun 19, 2023Peer-reviewedMolecular Biology

Circulating exosomes from Alzheimer's disease suppress VE-cadherin expression and induce barrier dysfunction in recipient brain microvascular endothelial cell

Jiani Bei, Ernesto G. Miranda-Morales, Qini Gan, Yuan Qiu, Sorosh Husseinzadeh, Jia Yi Liew, Qing Chang, Balaji Krishnan, Angelo Gaitas, Subo Yuan, Michelle Madden Felicella, Wei Qiao Qiu, Xiang Fang, Bin Gong

This study shows that Alzheimer's disease circulating exosomes reduce VE-cadherin expression and impair brain endothelial barrier function through RNA cargo-dependent mechanisms.

bioRxiv · Apr 3, 2023 · PreprintNeuroscience