Cold-induced Suspension and Resetting of Ca2+ and Transcriptional Rhythms in the Suprachiasmatic Nucleus Neurons
Ryosuke Enoki, Naohiro Kon, Kimiko Shimizu, Kenta Kobayashi, Sota Hiro, Ching-Pu Chang, Tatsuto Nakane, Hirokazu Ishii, Joe Sakamoto, Yoshifumi Yamaguchi, Tomomi Nemoto
This study shows that SCN neurons maintain circadian rhythms at moderate hypothermia but suspend them at deep hypothermia, with Ca2+ rhythms resetting faster than transcriptional rhythms upon rewarming.
iScience · Nov 3, 2023Peer-reviewedNeuroscience