Hirokazu Ishii

This paper introduces 2P-RESOLFT microscopy, achieving 205-nm lateral resolution to visualize previously unreported membrane protrusions in pancreatic beta cells.

This study uses quantum dot imaging temperature sensors to measure brain temperature in mice, revealing vascular cooling's role in protecting against heat stress in pathological conditions.

This paper develops an implantable microprism interface for deep-brain imaging with submicrometer resolution and wide-field two-photon microscopy.

This study investigates how Aβ dimers alter fast and localized calcium elevations in astrocytes, finding increased frequency and occupancy of calcium events mediated by P2Y1 receptors and ER Ca2+ release.

This study shows that SCN neurons maintain circadian rhythms at moderate hypothermia but suspend them at deep hypothermia, with Ca2+ rhythms resetting faster than transcriptional rhythms upon rewarming.