Joe Sakamoto

This paper introduces 2P-RESOLFT microscopy, achieving 205-nm lateral resolution to visualize previously unreported membrane protrusions in pancreatic beta cells.

The paper shows that Wntless restricts Notch signaling to balance neuron and gliocyte generation in zebrafish dorsal diencephalon.

This study investigates how Aβ dimers alter fast and localized calcium elevations in astrocytes, finding increased frequency and occupancy of calcium events mediated by P2Y1 receptors and ER Ca2+ release.

The paper investigates excessive chondrogenesis in Xenopus froglet blastemas during limb regeneration, finding it initiates at the medium bud stage and progresses spatially and temporally.

This study shows that SCN neurons maintain circadian rhythms at moderate hypothermia but suspend them at deep hypothermia, with Ca2+ rhythms resetting faster than transcriptional rhythms upon rewarming.

The paper shows that the shh limb enhancer MFCS1 is active in patterned limb regeneration in tadpoles but not in hypomorphic regeneration in froglets, suggesting epigenetic regulation is key.