Photoaged microplastics disrupt endothelial stretch-sensitive ion channels to impair calcium signaling and vascular integrity
Seul-Ki Park, Jae Min Cho, Enbo Zhu, Khoa Vu, Jing Wang, Peng Zhao, Aaron S. Romero, Matthew J. Campen, Srinivasa Reddy, Eliseo F. Castillo, Tzung K. Hsiai
This study shows photoaged microplastics impair endothelial calcium signaling and vascular integrity by disrupting Piezo1-Notch mechanotransduction.
bioRxiv · May 5, 2026 · PreprintCell Biology