The histone demethylase KDM3 prevents auto-immune piRNAs production in Drosophila
Karine Casier, Julie Autaa, Nathalie Gueguen, Valérie Delmarre, Pauline P. Marie, Stéphane Ronsseray, Clément Carré, Émilie Brasset, Laure Teysset, Antoine Boivin
The paper identifies KDM3 as a histone demethylase that prevents auto-immune piRNA production from gene-containing regions in Drosophila by inhibiting piRNA cluster formation.
Science Advances · Apr 7, 2023Peer-reviewedGenetics