Karine Casier

The paper identifies a threshold telomere length in telomerase-negative cells that triggers replicative senescence and genomic instability through dysfunction of the shortest telomere.

The paper identifies KDM3 as a histone demethylase that prevents auto-immune piRNA production from gene-containing regions in Drosophila by inhibiting piRNA cluster formation.

This paper shows that high temperature can induce a stable epigenetic conversion of a transgene cluster into an active piRNA-producing locus in flies, without maternal piRNA inheritance.