Mouse fertilization triggers a conserved transcription program in one-cell embryos
Maki Asami, Brian Lam, Martin Hoffmann, Toru Suzuki, Xin Lu, Matthew David VerMilyea, Naoko Yoshida, Marcella K.L. Ma, Kara Rainbow, Stefanie Braun, Nina Patwary, Giles S.H. Yeo, Christoph A. Klein, Anthony C.F. Perry
The paper shows that transcription starts much earlier in mouse and human one-cell embryos than previously thought, driven mainly by the maternal genome.
bioRxiv · Sep 15, 2020 · PreprintDevelopmental Biology