Aggregation-Dependent Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies
Ivan Talucci, Timon Leske, Hans‐Wolfgang Klafki, Hassan Mohammed Mehedi, Steiert Annik, Bárbara Morgado, Sebastian Bothe, van Werven Lars, Thomas Liepold, Jochen Walter, Hermann Schindelin, Jens Wiltfang, Oliver Wirths, Olaf Jahn, Hans Michael Maric
This study characterizes the binding and modification requirements of 20 anti-Aβ antibodies across different Aβ forms, revealing aggregation-dependent sequence and modification selectivity.
eLife · Feb 9, 2026Peer-reviewedBiochemistry