Author

Hans‐Wolfgang Klafki

Universitätsmedizin GöttingenORCID 0000-0002-8672-9032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Bárbara MorgadoiD· 2 shared Jens WiltfangiD· 2 shared Oliver WirthsiD· 2 shared Andrew Octavian SasmitaiD· 1 shared Bastian BuesiD· 1 shared Carolin Böhler· 1 shared Constanze DeppiD· 1 shared Erinne Cherisse OngiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Bárbara MorgadoORCID

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2 papers

Recent·Most cited

Aggregation-Dependent Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies

Ivan Talucci, Timon Leske, Hans‐Wolfgang Klafki, Hassan Mohammed Mehedi, Steiert Annik, Bárbara Morgado, Sebastian Bothe, van Werven Lars, Thomas Liepold, Jochen Walter, Hermann Schindelin, Jens Wiltfang, Oliver Wirths, Olaf Jahn, Hans Michael Maric

This study characterizes the binding and modification requirements of 20 anti-Aβ antibodies across different Aβ forms, revealing aggregation-dependent sequence and modification selectivity.

eLife · Feb 9, 2026Peer-reviewedBiochemistry

Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer's disease

Andrew Octavian Sasmita, Constanze Depp, T. I. Nazarenko, Ting Sun, Sophie B. Siems, Erinne Cherisse Ong, Yakum Bertrand Nkeh, Carolin Böhler, Xuan Yu, Bastian Bues, Lisa Evangelista, Shuying Mao, Bárbara Morgado, Zoe Y. Wu, Torben Ruhwedel, , Klaus‐Armin Nave

The paper shows oligodendrocytes contribute to amyloid-β plaques in Alzheimer's disease, but neurons are required for plaque formation.

Nature Neuroscience · Aug 5, 2024Peer-reviewedNeuroscience