The effects of acute Methylene Blue administration on cerebral blood flow and metabolism in humans and rats
Nisha Singh, Eilidh MacNicol, Ottavia Dipasquale, Karen Randall, David J. Lythgoe, Ndaba Mazibuko, Camilla Simmons, Pierluigi Selvaggi, Stephanie Stephenson, Federico Turkheimer, Diana Cash, Fernando O. Zelaya, Alessandro Colasanti
This study investigates the effects of acute Methylene Blue administration on cerebral blood flow and metabolism in humans and rats, finding dose-dependent reductions in CBF and metabolic rates contrary to initial hypotheses.
Journal of Cerebral Blood Flow & Metabolism · Feb 21, 2023Peer-reviewedNeuroscience