Nisha Singh

This study examines the brain phenotype of Dp1Tyb mice, a Down syndrome model, revealing neuroanatomical and biochemical alterations compared to wild-type controls.

This study investigates the effects of acute Methylene Blue administration on cerebral blood flow and metabolism in humans and rats, finding dose-dependent reductions in CBF and metabolic rates contrary to initial hypotheses.

This study examines GABAA and NMDA receptor density changes in MAM-treated rats and their behavioral correlates, finding reduced 5GABAAR and increased NMDA receptor densities linked to schizophrenia-like behaviors.

This study uses MRI and histology to identify structural and cellular changes in TDP-43 knock-in mice, linking them to ALS-FTD pathology and identifying PV+ interneuron loss as a potential biomarker.

This study shows chronic haloperidol increases [3H]-Ro15-4513 binding in rat hippocampus and [3H]-flumazenil binding across brain regions, suggesting antipsychotics may affect GABAAR availability.