Author

Ndaba Mazibuko

King's College LondonORCID 0000-0001-6701-2602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:imaging· 3 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

Fernando O. ZelayaiD· 3 shared Aikaterini FotopoulouiD· 2 shared Daniel MartinsiD· 2 shared Ottavia DipasqualeiD· 2 shared Uwe SchuschnigiD· 2 shared Yannis PaloyelisiD· 2 shared Alessandro ColasantiiD· 1 shared Alice E. OatesiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Fernando O. ZelayaORCID

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3 papers

Recent·Most cited

The effects of acute Methylene Blue administration on cerebral blood flow and metabolism in humans and rats

Nisha Singh, Eilidh MacNicol, Ottavia Dipasquale, Karen Randall, David J. Lythgoe, Ndaba Mazibuko, Camilla Simmons, Pierluigi Selvaggi, Stephanie Stephenson, Federico Turkheimer, Diana Cash, Fernando O. Zelaya, Alessandro Colasanti

This study investigates the effects of acute Methylene Blue administration on cerebral blood flow and metabolism in humans and rats, finding dose-dependent reductions in CBF and metabolic rates contrary to initial hypotheses.

Journal of Cerebral Blood Flow & Metabolism · Feb 21, 2023Peer-reviewedNeuroscience

Less is more: a dose-response account of intranasal oxytocin pharmacodynamics in the human brain

Daniel Martins, Katja Brodmann, Mattia Veronese, Ottavia Dipasquale, Ndaba Mazibuko, Uwe Schuschnig, Fernando O. Zelaya, Aikaterini Fotopoulou, Yannis Paloyelis

This study shows that lower doses of intranasal oxytocin have maximal effects on amygdala physiology, with subregion-specific responses and no disruption of cerebrovascular reactivity.

Progress in Neurobiology · Feb 2, 2022Peer-reviewedNeuroscience

Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

Daniel Martins, Ndaba Mazibuko, Fernando O. Zelaya, S. Vasilakopoulou, Joanna Loveridge, Alice E. Oates, Stefanos Maltezos, Mitul Ashok Mehta, Stephen J. Wastling, Matthew A. Howard, Grainne Mary McAlonan, Declan Murphy, Steven Williams, Aikaterini Fotopoulou, Uwe Schuschnig, Yannis Paloyelis

This study compares intranasal and intravenous oxytocin administration effects on regional cerebral blood flow, showing systemic OT increases drive amygdala perfusion changes and validating intranasal targeting of specific brain regions.

Nature Communications · Mar 3, 2020Peer-reviewedNeuroscience