Diana Cash

The paper uses MRI and transcriptomic data from a GD3 synthase-deficient mouse model to identify molecular correlates of brain structural differences.

This paper uses longitudinal MRI/MRS to study demyelination in a mouse model, showing dynamic and partially reversible pathology that correlates with histology.

The paper uses imaging transcriptomics in a mouse model of MSA to link MRI patterns with gene expression, identifying molecular correlates of neurodegeneration.

This study investigates the effects of mild perinatal hypoxia on cortical development in rats, finding disrupted excitatory-inhibitory circuit maturation and increased vulnerability in specific brain regions.

The paper shows that synaptotoxic forms of amyloid-beta and alpha-synuclein act through the same Wnt/PCP pathway to cause dendritic spine loss in neurodegenerative diseases.

This study finds no significant brain structural or functional differences in C3ar1-deficient mice across development, suggesting C3ar1 may not be critical for neurodevelopment.

The paper assesses consistency of rat fMRI results across 12 centers using a unified pipeline and identifies variability due to experimental differences.

This study shows that KDM5B deficiency in mice leads to autism-like behaviors and increased brain size, which can be mitigated by NMDAR antagonists.

This study examines the brain phenotype of Dp1Tyb mice, a Down syndrome model, revealing neuroanatomical and biochemical alterations compared to wild-type controls.

This study shows that reduced glucocorticoid responsiveness to stress causes multiple PTSD-related traits in rats, including fear extinction deficits, small hippocampal volume, and REMS disturbances.

EiDA is a method for analyzing dynamic functional connectivity in resting-state fMRI data from ageing rats, revealing reduced phase-locking intensity and structural complexity with age.

This study investigates the effects of acute Methylene Blue administration on cerebral blood flow and metabolism in humans and rats, finding dose-dependent reductions in CBF and metabolic rates contrary to initial hypotheses.

The paper shows that different behavioral patterns in mice lead to distinct brain connectivity patterns in an enriched environment.

This study uses diffusion MRI to detect neuroinflammation in vivo in rats after a lipopolysaccharide challenge, showing diffusivity changes correlate with microglial morphology.

This paper develops an optimization strategy for ex vivo diffusion imaging in rodent brains to improve signal-to-noise ratio and reduce acquisition time.

This study shows that deleting Erbb4 from PV+ interneurons in mice leads to neuroimaging changes similar to those seen in psychosis patients.

This study examines GABAA and NMDA receptor density changes in MAM-treated rats and their behavioral correlates, finding reduced 5GABAAR and increased NMDA receptor densities linked to schizophrenia-like behaviors.

The paper develops a rat brain age prediction algorithm using MRI and validates it through a healthy lifestyle intervention, showing reduced brain ageing with environmental enrichment and dietary restriction.

This study shows that subcutaneous NT3 infusion improves sensorimotor recovery in elderly rats after cortical stroke through corticospinal axon sprouting, not neuroprotection.

This paper demonstrates that multi-parametric manganese-enhanced MRI (MEMRI) can detect senile plaques in rodent AD models, showing manganese binds to plaques in 5xFAD mice but not TgF344-AD rats.

The paper shows REM and NREM sleep abnormalities and structural changes in GBA1 mice, linking them to RBD and alpha-synucleinopathy progression.

This study uses MRI and histology to identify structural and cellular changes in TDP-43 knock-in mice, linking them to ALS-FTD pathology and identifying PV+ interneuron loss as a potential biomarker.

This study shows chronic haloperidol increases [3H]-Ro15-4513 binding in rat hippocampus and [3H]-flumazenil binding across brain regions, suggesting antipsychotics may affect GABAAR availability.

This study investigates the role of TLR2 in neuroinflammatory responses in a rodent model of obstructive sleep apnea, linking it to behavioral and metabolic changes.

This study shows that delayed peripheral infusion of neurotrophin-3 improves sensorimotor recovery after ischemic stroke in rats by inducing spinal neuroplasticity.