Cryo-EM structures of the CDK11-cyclin L-SAP30BP complex reveal mechanisms of CDK11 regulation
Amy J. S. McGeoch, Victoria I. Cushing, Theodoros I. Roumeliotis, Nora Cronin, Stephen James Hearnshaw, Jyoti Sharma Choudhary, Claudio Alfieri, Basil J. Greber
The paper presents the cryo-EM structure of the CDK11-cyclin L-SAP30BP complex, revealing mechanisms of CDK11 regulation and inhibitor selectivity.
Nature Communications · Apr 25, 2026Peer-reviewedMolecular Biology