HTLV-1 intasome recruits the PP2A-B56 holoenzyme and restricts its phosphatase activity
Jordan James Minnell, Emma K. Punch, Teresa Vanzo, Roghaiyeh Safari, Nora Cronin, P.G. Cherepanov, Goedele N. Maertens
The paper shows HTLV-1 integrase recruits PP2A-B56 holoenzyme, structurally inhibiting its phosphatase activity without affecting infection.
bioRxiv · May 4, 2026 · PreprintMicrobiology