Author
Institute of Cancer ResearchORCID 0000-0003-3215-1607Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
R P Young, Amy J. S. McGeoch, Matthew Jessop…·Claudio Alfieri
The paper introduces synthetic peptides to improve cryo-EM grid preparation for multi-subunit protein complexes by reducing disassembly and preferred orientation.
Amy J. S. McGeoch, Victoria I. Cushing, Theodoros I. Roumeliotis…·Basil J. Greber
The paper presents the cryo-EM structure of the CDK11-cyclin L-SAP30BP complex, revealing mechanisms of CDK11 regulation and inhibitor selectivity.
Lillian Wu, Karen A. Lane, Reyhan Muhammad…·Jessica A. Downs
This study identifies a non-centromeric role for CENP-B in binding hairpin motifs in chromosome arms, leading to dysregulated gene expression upon depletion.
Mercedes Pardo, Chiara Marcozzi, Karen A. Lane…·Jyoti Sharma Choudhary
This study uses PRISMA to identify and map novel ARID1A interactions at high sequence resolution, revealing new interactors and a regulatory mechanism involving CDK2 phosphorylation.
Mandy S. M. Wan, Reyhan Muhammad, Marios G. Koliopoulos…·Claudio Alfieri
The paper presents the structure of the SIN3B histone deacetylase complex and elucidates its mechanism of substrate recognition and catalysis.