Combining in vivo 2-photon imaging with photoactivatable fluorescent labeling reveals strikingly low rates of mitochondrial dynamics in skeletal muscle.
Colleen L. O’Reilly, Arik Davidyan, Katarzyna Cizio, Stephen M. Doidge, Matthew P. Bubak, Agnieszka Borowik, Tommy L. Lewis, Benjamin F. Miller
This study uses in vivo 2-photon imaging and photoactivatable fluorescent labeling to show that mitochondrial dynamics in skeletal muscle are slower in vivo than previously thought, with age-related differences and exercise-induced increases.
Medicine & Science in Sports & Exercise · May 1, 2025Peer-reviewedPhysiology