Arik Davidyan

Combining in vivo 2-photon imaging with photoactivatable fluorescent labeling reveals strikingly low rates of mitochondrial dynamics in skeletal muscle.

This study uses in vivo 2-photon imaging and photoactivatable fluorescent labeling to show that mitochondrial dynamics in skeletal muscle are slower in vivo than previously thought, with age-related differences and exercise-induced increases.

Metformin treatment results in distinctive skeletal muscle mitochondrial remodeling in rats with different intrinsic aerobic capacities

This study shows metformin induces different mitochondrial remodeling in rat skeletal muscle based on baseline aerobic capacity and muscle type.