An allosteric network governs Tom70 conformational dynamics to coordinate mitochondrial import
Maxwell J. Bachochin, Kelly L. McGuire, B. Cook, Qiaozhen Ye, Steven Silletti, Kevin D. Corbett, Elizabeth A. Komives, Mark A. Herzik
This study reveals the conformational dynamics of Tom70 through structural and computational analyses, showing how its allosteric network coordinates mitochondrial protein import and is modulated by viral interactions.
Structure · Dec 11, 2025Peer-reviewedBiophysics