B. Cook

The paper introduces SurfACT, a surfactant cocktail that reduces air-water interface artifacts in cryoEM, improving particle distribution and map completeness for four proteins.

This study reveals the conformational dynamics of Tom70 through structural and computational analyses, showing how its allosteric network coordinates mitochondrial protein import and is modulated by viral interactions.

ANTIDOTE improves cryoEM particle sorting by using metadata-driven neural networks, enhancing reconstruction quality and reducing manual curation efforts.

This paper presents a streamlined method for (an)aerobic vitrification of oxygen-sensitive proteins using an automated device, enabling high-resolution cryoEM structure determination.

The paper shows that short 5' UTRs in viral mRNAs are recognized by the IFIT2-IFIT3 complex, leading to translation inhibition and antiviral activity.

This paper describes the use of the chameleon device for tuning ice thickness to improve cryoEM grid quality and image quality.